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Strikeforce: Los Angeles was held on June 16, 2010 at Nokia Theatre in Los Angeles, California.
Strikeforce: Los Angeles Previews & Predictions
| Match | Winner | Loser | Method | Round | Time |
| 1 | Hugo Sandoval | Marcus Kowal | TKO (Punches) | 2 | 0:43 |
| 2 | Jeremy Umphries | R.J. Clifford | Technical Submission (Rear-Naked Choke) | 2 | 2:27 |
| 3 | Karl James Noons | Conor Heun | Decision (Split) | 3 | 5:00 |
| 4 | Tim Kennedy | Trevor Prangley | Submission (Rear-Naked Choke) | 1 | 3:35 |
| 5 | Evangelista Santos | Marius Zaromskis | TKO (Punches) | 1 | 2:38 |
| 6 | Renato Sobral | Robbie Lawler | Decision (Unanimous) | 3 | 5:00 |
