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Strikeforce: Melendez vs. Masvidal took place on December 17, 2011 at the Valley View Casino Center in San Diego, California.
Strikeforce: Melendez vs. Masvidal officially drew 2,995 attendees for a $154,075 live gate.
Strikeforce: Melendez vs. Masvidal Post Fight Analysis
Strikeforce: Melendez vs. Masvidal Tapology Strikeforce: Melendez vs. Masvidal Pre-Fight Analysis
| Match | Winner | Loser | Method | Round | Time |
| 1 | Herman Terrado | Chris Brown | Submission (Armbar) | 3 | 4:05 |
| 2 | Eddie Mendez | Fernando Gonzalez | Decision (Split) | 3 | 5:00 |
| 3 | Devin Cole | Gabriel Salinas-Jones | Decision (Unanimous) | 3 | 5:00 |
| 4 | Roger Bowling | Jerron Peoples | KO (Punches) | 1 | 0:42 |
| 5 | Caros Fodor | Justin Wilcox | KO (Punches) | 1 | 0:13 |
| 6 | K.J. Noons | Billy Evangelista | Decision (Unanimous) | 3 | 5:00 |
| 7 | Gegard Mousasi | Ovince St. Preux | Decision (Unanimous) | 3 | 5:00 |
| 8 | Cristiane Santos | Hiroko Yamanaka | No Decision – Overturned by CSAC | 1 | 0:16 |
| 9 | Gilbert Melendez | Jorge Masvidal | Decision (Unanimous) | 5 | 5:00 |
* Cristiane Santos originally defeated Hiroko Yamanaka via TKO (Punches).
