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UFC on Fox 1: Velasquez vs. Dos Santos took place on November 12, 2011 at the Honda Center in Anaheim, California. The event will be the fifth that the UFC has hosted in Anaheim.
This card marked the UFC’s debut on the Fox Network. The main event was televised live on Fox and the 10 preliminary bouts were streamed live on Facebook and Fox.com.
UFC on FOX: Velasquez vs. Dos Santos officially drew an attendance figure of 11,607 and a live gate of $1,072,187. The event scored a 3.1 household rating with an average audience of 5.7 million viewers and peaked with 8.8 million viewers.
UFC on Fox 1 Post Fight Analysis
UFC on Fox 1 Tapology UFC on Fox 1 Pre-Fight Analysis
| Match | Winner | Loser | Method | Round | Time |
| 1 | Aaron Rosa | Matt Lucas | Decision (Majority) | 3 | 5:00 |
| 2 | Mike Pierce | Paul Bradley | Decision (Split) | 3 | 5:00 |
| 3 | Alex Caceres | Cole Escovedo | Decision (Unanimous) | 3 | 5:00 |
| 4 | Robert Peralta | Mackens Semerzier | NC (Accidental Head-butt) | 3 | 1:54 |
| 5 | Darren Uyenoyama | Norifumi Yamamoto | Decision (Unanimous) | 3 | 5:00 |
| 6 | DaMarques Johnson | Clay Harvison | KO (Punches) | 1 | 1:34 |
| 7 | Ricardo Lamas | Cub Swanson | Submission (Arm-Triangle Choke) | 2 | 2:16 |
| 8 | Dustin Poirier | Pablo Garza | Submission (Brabo Choke) | 2 | 1:32 |
| 9 | Ben Henderson | Clay Guida | Decision (Unanimous) | 3 | 5:00 |
| 10 | Junior dos Santos | Cain Velasquez | TKO (Punches) | 1 | 1:04 |
